Efficacy and Effectiveness of High-Dose Influenza Vaccine for Older Adults: A Systematic Review and Meta-Analysis

1464. Influenza Vaccine Effectiveness among Elderly and Non-Elderly Adults Aged ≥45 Years in the United States, 2011–2012 to 2015–2016 Fiona P. Havers, MD, MHS; Kate Russell, MD, MPH; Jessie Chung, MPH; Arnold S. Monto, MD, FIDSA; Emily T. Martin, MPH, PhD; Edward A. Belongia, MD; Huong Q. McLean, PhD, MPH; Manjusha Gaglani, MBBS; Kempapura Murthy, MBBS, MPH; Richard K. Zimmerman, MD MPH, FIDSA; Mary Patricia Nowalk, PhD; Michael L. Jackson, PhD, MPH; Lisa A. Jackson, MD, MPH, FIDSA and Brendan L. Flannery, PhD; Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia, Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, Marshfield Clinic Research Institute, Marshfield, Wisconsin, Marshfield Clinic R esearch Foundation, Marshfield, Wisconsin, Pediatrics; Pediatric Infectious Diseases, Baylor Scott & White Health; Texas A&M University HSC COM, Temple, Texas, Baylor Scott & White Health, Temple, Texas, University of Pittsburgh, Pittsburgh, Pennsylvania, Kaiser Permanente Washington Health Research Institute, Seattle, Washington